IDENTIFICATION OF THE ROLE OF SNARE PROTEINS IN RAAV VECTOR PRODUCTION THROUGH INTERACTION WITH THE VIRAL MAAP

Identification of the role of SNARE proteins in rAAV vector production through interaction with the viral MAAP

Adeno-associated virus (AAV) expresses a membrane-associated accessory protein (MAAP), a small nonstructural protein, that facilitates AAV secretion out of the plasma membrane through an association with extracellular vesicles during AAV egress.Here, we investigated the host proteins that interact with AAV2 Body Washes MAAP (MAAP2) using APEX2-medi

read more